{"id":378,"date":"2024-05-13T00:21:36","date_gmt":"2024-05-12T22:21:36","guid":{"rendered":"https:\/\/sfsb.farm.unipi.it\/?page_id=378"},"modified":"2024-05-15T23:15:43","modified_gmt":"2024-05-15T21:15:43","slug":"chiaverini-lorenzo","status":"publish","type":"page","link":"https:\/\/sfsb.farm.unipi.it\/en\/cicli-attivi\/chiaverini-lorenzo\/","title":{"rendered":"Chiaverini Lorenzo"},"content":{"rendered":"<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"200\" height=\"230\" src=\"https:\/\/sfsb.farm.unipi.it\/wp-content\/uploads\/2024\/05\/Chiaverini.jpg\" alt=\"\" class=\"wp-image-359\" srcset=\"https:\/\/sfsb.farm.unipi.it\/wp-content\/uploads\/2024\/05\/Chiaverini.jpg 200w, https:\/\/sfsb.farm.unipi.it\/wp-content\/uploads\/2024\/05\/Chiaverini-10x12.jpg 10w, https:\/\/sfsb.farm.unipi.it\/wp-content\/uploads\/2024\/05\/Chiaverini-130x150.jpg 130w\" sizes=\"auto, (max-width: 200px) 100vw, 200px\" \/><\/figure>\n\n\n\n<div style=\"height:10px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Contacts<\/strong>: <\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"mailto:lorenzo.chiaverini@phd.unipi.it\">lorenzo.chiaverini@phd.unipi.it<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Supervisor(s)<\/strong>:<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Professor Tiziano Marzo and Diego La Mendola<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>PhD project Title<\/strong>:<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Biocompatible smart nanovectors for the chemotherapy treatment of prostate cancer<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Abstract of the PhD project<\/strong>:<\/p>\n\n\n\n<p class=\"has-text-align-left justify-text wp-block-paragraph\">The main objective of my PhD research project is to improve the combination chemotherapy for prostate cancer, developing PLGA-PEG fluorescent biocompatible nanovectors (NVs) for drugs loading, decorated with angiogenin-mimicking peptides, leading to a double effect: impairment of cancer cells angiogenesis and drugs\u2019 delivery at the tumour site. Prostate cancer is among the most common cancers in men. It has a poor prognosis in case of relapse or late-stage detection, making urgent improved therapies. Therefore, the aim is to create nanovectors able to enhance the drugs\u2019 intake and the therapeutic effects through targeted delivery, and to reduce\/abolish the intake of the plasma circulating Angiogenin into the prostate cancerous cells.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Publications link: <\/strong><\/p>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-8f761849 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<figure class=\"wp-block-image size-full is-resized\"><a href=\"https:\/\/www.scopus.com\/authid\/detail.uri?authorId=57658056600\" target=\"_blank\" rel=\"noreferrer noopener\"><img loading=\"lazy\" decoding=\"async\" width=\"120\" height=\"36\" src=\"https:\/\/sfsb.farm.unipi.it\/wp-content\/uploads\/2024\/04\/Scopus-2.png\" alt=\"\" class=\"wp-image-184\" style=\"width:auto;height:20px\" srcset=\"https:\/\/sfsb.farm.unipi.it\/wp-content\/uploads\/2024\/04\/Scopus-2.png 120w, https:\/\/sfsb.farm.unipi.it\/wp-content\/uploads\/2024\/04\/Scopus-2-18x5.png 18w\" sizes=\"auto, (max-width: 120px) 100vw, 120px\" \/><\/a><\/figure>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<figure class=\"wp-block-image size-full is-resized\"><a href=\"https:\/\/orcid.org\/0000-0003-4857-9819\"><img loading=\"lazy\" decoding=\"async\" width=\"120\" height=\"36\" src=\"https:\/\/sfsb.farm.unipi.it\/wp-content\/uploads\/2024\/05\/Orcid.png\" alt=\"\" class=\"wp-image-497\" style=\"width:auto;height:20px\" srcset=\"https:\/\/sfsb.farm.unipi.it\/wp-content\/uploads\/2024\/05\/Orcid.png 120w, https:\/\/sfsb.farm.unipi.it\/wp-content\/uploads\/2024\/05\/Orcid-18x5.png 18w\" sizes=\"auto, (max-width: 120px) 100vw, 120px\" \/><\/a><\/figure>\n<\/div>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>Contacts: lorenzo.chiaverini@phd.unipi.it Supervisor(s): Professor Tiziano Marzo and Diego La Mendola PhD project Title: Biocompatible smart nanovectors for the chemotherapy treatment of prostate cancer Abstract of the PhD project: The main objective of my PhD research project is to improve the combination chemotherapy for prostate cancer, developing PLGA-PEG fluorescent biocompatible nanovectors&#8230;<\/p>\n<p class=\"continue-reading-button\"> <a class=\"continue-reading-link\" href=\"https:\/\/sfsb.farm.unipi.it\/en\/cicli-attivi\/chiaverini-lorenzo\/\">Continue reading<i class=\"crycon-right-dir\"><\/i><\/a><\/p>","protected":false},"author":1,"featured_media":0,"parent":152,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-378","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/sfsb.farm.unipi.it\/en\/wp-json\/wp\/v2\/pages\/378","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/sfsb.farm.unipi.it\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/sfsb.farm.unipi.it\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/sfsb.farm.unipi.it\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/sfsb.farm.unipi.it\/en\/wp-json\/wp\/v2\/comments?post=378"}],"version-history":[{"count":2,"href":"https:\/\/sfsb.farm.unipi.it\/en\/wp-json\/wp\/v2\/pages\/378\/revisions"}],"predecessor-version":[{"id":519,"href":"https:\/\/sfsb.farm.unipi.it\/en\/wp-json\/wp\/v2\/pages\/378\/revisions\/519"}],"up":[{"embeddable":true,"href":"https:\/\/sfsb.farm.unipi.it\/en\/wp-json\/wp\/v2\/pages\/152"}],"wp:attachment":[{"href":"https:\/\/sfsb.farm.unipi.it\/en\/wp-json\/wp\/v2\/media?parent=378"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}