Contacts:
francesca.caricchio@phd.unipi.it
Supervisor(s):
Prof. Anna Maria Piras and Dott. Carlo Michelini
PhD project Title:
Formulations for minimally invasive interventions in the repair of skin and joint tissue
Abstract of the PhD project:
This project aims to develop innovative polymeric devices for aesthetic medicine and biomedical applications. As examples, poly-L-lactic acid (PLLA) microparticle for dermal and joint tissue regeneration will be investigated. Microparticles will be prepared through emulsion and nanoprecipitation techniques, integrating hydroxyapatite and post-biotics to enhance tissue regeneration. Morphology, physicochemical properties, and degradation profiles will be studied to ensure biocompatibility and safety. Needle-free delivery systems, such as jet injectors, will be designed to optimize patient comfort and therapeutic efficacy. Cellular studies will evaluate cytotoxicity and collagen synthesis, promoting minimally invasive treatments to improve patient quality of life and clinical outcomes.
Publications link:
IT_IT 
EN