Contacts:
Supervisor(s):
Professor MInunni and Prof Ravelet
PhD project Title:
Detection of a clinical biomarker via copper nanoclusters and aptamers-based biosensor
Abstract of the PhD project:
Arginine-vasopressin (ADH) is a very important clinical biomarker for the diagnosis of diseases such as diabetes insipidus, psychogenic water intoxication, and hyponatremia.
The quantitative measurement of ADH in biological fluids is usually performed via a competitive radioimmunoassay approach, which suffers from limited reproducibility and sensitivity. The aim of my PhD project is to develop a novel solution-based diagnostic tool based on the high selectivity of aptamers, which will be used as molecular recognition elements for vasopressin, and the high sensitivity and easy synthesis associated with DNA-templated copper nanoclusters.
Publications link:
IT_IT 
EN